Eligibility

Local study conflicts

• None

Inclusion Criteria:

• Aged 16 years old or over
• A current clinical diagnosis of cellulitis at any body site except the orbit (periorbital/orbital cellulitis)
• Able to provide informed consent
• People of child-bearing* potential must be willing to:
• Use an effective method of contraception** (and must agree to continue 3 months after the last dose of the IMP)
• Inform the trial team if pregnancy occurs during trial participation

Exclusion Criteria:

• Orbital or periorbital cellulitis, surgical site infection, or planned surgical management (e.g abscess) as managed under a different clinical pathway
• Allergy to dexamethasone
• Contraindication to dexamethasone due to concurrent medication (e.g. cobicistat)
• Has known current invasive fungal infection**
• Has known current gastric or duodenal ulceration
• Already on corticosteroids
• Unable to take oral medication
• Lack of capacity
• Inability to complete follow-up procedures
• Prisoner*
• Pregnant***, breastfeeding, or planning to conceive in next 3 months