The Dexacell study is not yet open to recruitment.
Eligibility
Local study conflicts
Inclusion Criteria:
- Aged 16 years old or over
- A current clinical diagnosis of cellulitis at any body site except the orbit (periorbital/orbital
cellulitis)
- Able to provide informed consent
- People of child-bearing* potential must be willing to:
- Use an effective method of contraception** (and must agree to continue 3 months after the last dose of
the IMP)
- Inform the trial team if pregnancy occurs during trial participation
Exclusion Criteria:
- Orbital or periorbital cellulitis, surgical site infection, or planned surgical management (e.g abscess) as
managed under a different clinical pathway
- Allergy to dexamethasone
- Contraindication to dexamethasone due to concurrent medication (e.g. cobicistat)
- Has known current invasive fungal infection**
- Has known current gastric or duodenal ulceration
- Already on corticosteroids
- Unable to take oral medication
- Lack of capacity
- Inability to complete follow-up procedures
- Prisoner*
- Pregnant***, breastfeeding, or planning to conceive in next 3 months